The healing process of vertebral body fracture in Wistar rats: creation of an animal model and demonstration of the impact of anterolateral vascularization disruption on bone healing
Disruption of the anterolateral vascular supply significantly delays healing in L1 vertebral body fractures in rats, evidenced by slower phase transitions and reduced bone maturation. These findings underscore the essential role of vascularization in successful vertebral repair and suggest it should be considered in future therapeutic strategies.
Authors
- Diogo Lino Moura (ORCID: https://orcid.org/0000-0003-4037-2442)
- Sara Alves
- Diogo Pais (ORCID: https://orcid.org/0000-0001-9837-0197)
- José Casanova (ORCID: https://orcid.org/0000-0002-0561-0364)
- Rui Almeida (ORCID: https://orcid.org/0000-0002-7844-0167)
- Diogo Casal (ORCID: https://orcid.org/0000-0002-5537-9340)
- António Bernardes
Institutions
- University of Coimbra (PT)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- Journal of Spine Surgery
- Published
- 2025-09-01
- DOI
- https://doi.org/10.21037/jss-25-55
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00