Innovative Use of Corticioid Fungi Derivatives for Therapy of Antibiotics Resistance to Robust Gram Positive and Gram Negative-Bacteria

Having reviewed the role of different significant phage's in eradication of escalating antibiotics resistance and eradication of multi drug resistant Tuberculosis (MDR) epidemic in India resulting from etiopathogenetisc Mycobacterium Tuberculosis agent.The aim of this short communication'' is emphasizing the part of corticioid fungi in treating future infections resulting from drug resistant bacteria.As per authors from Poland, documented the extracts from 58 species of corticioid fungi (phylum Basidiomycota), which basically belonged to the orders Hymenochaetales, Polyporales as well as Russulales, were evaluated for their hampering activity against five species of bacteria: Corynebacterium striatum, Haemophilus influenzae, Klebsiella pneumoniae, Pseudomonas aeruginosa, in addition to Staphylococcusaureus14 fungal species investigated, possessed moderate activity against just two bacteria, P. aeruginosa in addition to C. striatum; 17 species possessed activity against just C. striatum.The total hampering was found with quantities of extract 25 or 50 mg/mL.Thereby putative information whose presence has been accepted since 1940's, however later not pursued has resurfaced with escalating antibiotics resistance, thereby dead trees having such corticioid fungi possessed significant bacteria in contrast to ones without corticioid fungi.Thereby this brings hope for replacing antibiotics with resistance developed due to misuse of antibiotics by we physicians, in generating therapies from derivatives of such corticioid fungi.Hopefully this would be translated in clinical scenario to combat antibiotics resistance or MDR.