Evaluation of the incidence and risk factors of acute renal injury according to the prifle criteria in children with ventricular septal defect (VSD) and atrioventricular septal defect (AVSD) after cardiovascular interference

Aims: We aimed to determine the incidence and risk factors of acute kidney injury (AKI) according to pRIFLE (Risk, Injury, Failure, Loss, Endstage) criteria and to evaluate its effect on prognosis in patients followed up in intensive care unit after interventions for heart disease. Methods: The study included 84 patients who underwent surgery for VSD and AVSD between January 2016 and September 2016 in the Pediatric Cardiovascular Surgery Clinic of Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital. Patients were prospectively analyzed. Primary disease, demographic data, duration of intensive care and hospital stay, duration of follow-up on ventilator, urine output, vital signs, intraoperative data, primary and secondary problems, and renal function tests were recorded. Results: Among the patients, 35 were male, 49 were female, 30 were diagnosed with AVSD and 54 with VSD. pRIFLE classification revealed AKI in 19 patients. When the AKI (+) and non-AKI (+) groups were compared, no significant difference was found between the duration of cardiopulmonary bypass (CPB) in the AKI(+) group, while hypothermia levels were significantly lower (p=0.003). Mortality and length of hospital stay were significantly higher in the AKI(+) group. Conclusion: AKI is a serious complication in pediatric cardiac surgery patients. The presence and extent of damage is closely related to morbidity and mortality. The use of an inexpensive, easily applicable method such as pRIFLE criteria is recommended for the detection and grading of AKI.