A rare case of high-grade synovial sarcoma of the hindfoot

Aim To report our personal experience in hindfoot reconstruction using an anterolateral thigh (ALT) free flap following radical resection of a high-grade synovial sarcoma. Methods The patient underwent clinical and imaging assessments, and a biopsy of the lesion confirmed the diagnosis of synovial sarcoma (SS) of the hindfoot. A multidisciplinary team was involved to define the most appropriate therapeutic strategy. Results After radical resection of the tumor mass, soft tissue coverage of the extensive skin defect was achieved using an ALT free flap. No local recurrences were observed during the follow-up period. At approximately twenty-four months after surgical treatment, the patient is able to ambulate independently, with no significant limitations in daily activities. Conclusion The complex management of this rare disease requires a dedicated reference centre for foot and ankle surgery, supported by a multidisciplinary team including expert orthopaedic and plastic surgeons, as well as specialized oncologists, to ensure accurate diagnosis and appropriate treatment.

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Publication Details

Journal
Medicinski Glasnik
Published
2025-08-25
DOI
https://doi.org/10.17392/1967-22-02
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
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article

A rare case of high-grade synovial sarcoma of the hindfoot

Nicola Mondanelli, Elisa Troiano, Camillo Fulchignoni, Chiara Comisi et al.
Medicinski Glasnik
Sarcoma Diagnosis and Treatment
article

A rare case of high-grade synovial sarcoma of the hindfoot

Nicola Mondanelli, Elisa Troiano, Camillo Fulchignoni, Chiara Comisi, Elisabetta Pataia, Carlo Perisano, Giulio Maccauro, Tommaso Greco, Antonio Mascio, Francesco Farine
article en

Abstract

Aim To report our personal experience in hindfoot reconstruction using an anterolateral thigh (ALT) free flap following radical resection of a high-grade synovial sarcoma. Methods The patient underwent clinical and imaging assessments, and a biopsy of the lesion confirmed the diagnosis of synovial sarcoma (SS) of the hindfoot. A multidisciplinary team was involved to define the most appropriate therapeutic strategy. Results After radical resection of the tumor mass, soft tissue coverage of the extensive skin defect was achieved using an ALT free flap. No local recurrences were observed during the follow-up period. At approximately twenty-four months after surgical treatment, the patient is able to ambulate independently, with no significant limitations in daily activities. Conclusion The complex management of this rare disease requires a dedicated reference centre for foot and ankle surgery, supported by a multidisciplinary team including expert orthopaedic and plastic surgeons, as well as specialized oncologists, to ensure accurate diagnosis and appropriate treatment.

Medicinski GlasnikVol. 22(2)
University of Siena (IT), Università Cattolica del Sacro Cuore (IT), Agostino Gemelli University Polyclinic (IT), Azienda Ospedaliero-Universitaria Careggi (IT), Link Campus University (IT)
Openalex Percentile: Top 65%
Sarcoma Diagnosis and Treatment
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