The people behind the papers – Hannah Brown and Sean Ryder

MEX-3 is a conserved RNA-binding protein that is required for oocyte maturation and anterior cell fate specification during early embryogenesis in Caenorhabditis elegans. In their work, Sean Ryder and colleagues show that the 3' untranslated region (3'UTR) of mex-3 is essential for oocyte maturation and embryonic morphogenesis in worms under thermal stress. To find out more about their work, we spoke to the first author, Hannah Brown, and the corresponding author, Sean Ryder, Professor and Vice Chair for Outreach, Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, USA.

Publication Details

Journal
Development
Published
2025-09-01
DOI
https://doi.org/10.1242/dev.205195
Primary Topic
Genetics, Aging, and Longevity in Model Organisms
Type
article
Field-Weighted Citation Impact
0.00
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article

The people behind the papers – Hannah Brown and Sean Ryder

Development
Genetics, Aging, and Longevity in Model Organisms
article

The people behind the papers – Hannah Brown and Sean Ryder

article en

Abstract

MEX-3 is a conserved RNA-binding protein that is required for oocyte maturation and anterior cell fate specification during early embryogenesis in Caenorhabditis elegans. In their work, Sean Ryder and colleagues show that the 3' untranslated region (3'UTR) of mex-3 is essential for oocyte maturation and embryonic morphogenesis in worms under thermal stress. To find out more about their work, we spoke to the first author, Hannah Brown, and the corresponding author, Sean Ryder, Professor and Vice Chair for Outreach, Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, USA.

DevelopmentVol. 152(17)
Openalex Percentile: Top 79%
Genetics, Aging, and Longevity in Model Organisms
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The people behind the papers – Hannah Brown and Sean Ryder · Development (2025) | TGRS Research Map | TGRS