Goat-derived hyperimmune colostrum and milk following vaccination with live-attenuated and inactivated porcine epidemic diarrhea virus: Safety and immunogenicity evaluation
Vaccination of pregnant goats with live-attenuated or inactivated PEDV vaccines is safe and induces PEDV-specific antibodies in colostrum and milk. The live-attenuated vaccine generated the highest titers, indicating potential for producing goat-derived hyperimmune colostrum as an alternative passive immunization strategy for neonatal piglets. Field trials are warranted to confirm protective efficacy and explore integration into PEDV control programs.
Authors
- Alongkot Boonsoongnern (ORCID: https://orcid.org/0000-0002-4062-2707)
- Yonlayong Woonwong (ORCID: https://orcid.org/0009-0004-3968-614X)
- Prapassorn Boonsoongnern (ORCID: https://orcid.org/0000-0002-2553-6835)
- Manakorn Sukmak (ORCID: https://orcid.org/0000-0003-4625-0470)
- Niorn Ratanapob (ORCID: https://orcid.org/0000-0002-0937-5971)
- Pimpakarn Suwan (ORCID: https://orcid.org/0009-0003-3682-4511)
- Poonnika Suvannabha
Institutions
- Kasetsart University (TH)
Publication Details
- Journal
- Veterinary World
- Published
- 2025-09-01
- DOI
- https://doi.org/10.14202/vetworld.2025.2689-2698
- Citations
- 1
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.19
Funders
- National Science and Technology Development Agency
- Kasetsart University