Molecular methods to diagnose pertussis: a case of confusion with <i>Bordetella bronchiseptica</i>

This case, where the presence of <i>ptxP</i> was confirmed by whole genome sequencing in an isolate of <i>B. bronchiseptica</i>, highlights a caveat to the molecular diagnosis of pertussis and emphasizes the importance of understanding gene targets to interpret results when false positive detections are suspected.

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Publication Details

Journal
ASM Case Reports
Published
2025-09-09
DOI
https://doi.org/10.1128/asmcr.00084-24
Citations
1
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
1.18
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article

Molecular methods to diagnose pertussis: a case of confusion with Bordetella bronchiseptica

Rebekah E. Dumm, Gautam Dantas, Esse M. Evbuomwan, Christopher M. Zarbock et al.
1 citations
ASM Case Reports
Bacterial Infections and Vaccines
1.18
article

Molecular methods to diagnose pertussis: a case of confusion with Bordetella bronchiseptica

Rebekah E. Dumm, Gautam Dantas, Esse M. Evbuomwan, Christopher M. Zarbock, Melissa Shenep
article en
1 citations

Abstract

This case, where the presence of <i>ptxP</i> was confirmed by whole genome sequencing in an isolate of <i>B. bronchiseptica</i>, highlights a caveat to the molecular diagnosis of pertussis and emphasizes the importance of understanding gene targets to interpret results when false positive detections are suspected.

ASM Case ReportsVol. 1(6)
University of Washington (US), Washington University in St. Louis (US), Center for Genomic Science (IT)
Openalex Percentile: Top 18%
Bacterial Infections and Vaccines
1.18
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