Visualization of Water Dynamics on the Rat Cerebral Surface Using Direct Infusion of <sup>17</sup>O-Labeled Water into the Subarachnoid Space and Proton MRI [Presidential Award Proceedings]
We investigated the feasibility of visualizing water dynamics on the rat cerebral surface by direct injection of 17O-labeled water into the subarachnoid space of the cerebral cortex. We observed its dynamics on the rat cerebral surface, providing potential insights into the glymphatic hypothesis.
Authors
- Naoya Kinota (ORCID: https://orcid.org/0000-0002-9030-9671)
- Kohsuke Kudo (ORCID: https://orcid.org/0000-0001-5351-9242)
- Yoshitaka Bito (ORCID: https://orcid.org/0000-0003-4671-9347)
- Hiroyuki Kameda (ORCID: https://orcid.org/0000-0003-3667-4085)
- Daisuke Kato (ORCID: https://orcid.org/0000-0003-1710-4319)
- Takaaki Fujii
- Minghui Tang (ORCID: https://orcid.org/0000-0003-3310-2962)
Institutions
- Hokkaido University (JP)
- University of Dental Medicine (MM)
- Hokkaido University Hospital (JP)
Publication Details
- Journal
- Japanese Journal of Magnetic Resonance in Medicine
- Published
- 2025-08-15
- DOI
- https://doi.org/10.2463/jjmrm.2025-1844
- Primary Topic
- Atomic and Subatomic Physics Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00