Long‐Term Treadmill Exercise and Voluntary Running Pre‐Training Attenuates Vascular Dementia‐Related Pathology by Regulating Hippocampal Structural Synaptic Plasticity in a Rat Model
Both treadmill exercise and voluntary running improve cognitive function and ameliorate anxious-depressive-like behaviors in VD rat models. These therapeutic effects are mediated through enhanced synaptic structural plasticity in the hippocampal region of VD rats.
Authors
- Kunxia Su (ORCID: https://orcid.org/0000-0002-6519-856X)
- Yujiao Li (ORCID: https://orcid.org/0000-0002-1933-8779)
- Yuxuan Li (ORCID: https://orcid.org/0000-0002-4665-1816)
- Linlin Zhang
Institutions
- Zhongyuan University of Technology (CN)
- First Affiliated Hospital of Henan University (CN)
- Henan Normal University (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/brb3.70833
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00