Age-Stratified Reference Ranges for Directly Measured Serum Free Testosterone in Community-Dwelling and Healthy Men
This study provides age-stratified reference ranges for mFT in adult men, established in the largest cohort to date, using published methodology. Our results also show that mFT levels are influenced by age and BMI. Future work should focus on whether age-stratified or reference ranges for young men should be employed, and how mFT can best be implemented in clinical practice including the improved application of calculated FT.
Authors
- Bruno Lapauw (ORCID: https://orcid.org/0000-0002-1584-4965)
- Tim Reyns
- Nick Narinx (ORCID: https://orcid.org/0000-0002-7342-8724)
- Tom Fiers (ORCID: https://orcid.org/0000-0003-1398-5489)
- Joeri Walravens (ORCID: https://orcid.org/0000-0001-5159-3238)
- Leen Antonio (ORCID: https://orcid.org/0000-0002-1079-2860)
- Gido Snaterse (ORCID: https://orcid.org/0000-0002-1393-9602)
- Dirk Vanderschueren (ORCID: https://orcid.org/0000-0003-1395-0104)
- Katleen Van Uytfanghe (ORCID: https://orcid.org/0000-0001-8195-150X)
- Frederick C. W. Wu (ORCID: https://orcid.org/0000-0002-7005-4798)
- Jean‐Marc Kaufman (ORCID: https://orcid.org/0000-0002-1400-6812)
Institutions
- HOGENT University of Applied Sciences and Arts (BE)
- Ghent University Hospital (BE)
- University of Manchester (GB)
- Ghent University (BE)
- KU Leuven (BE)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1210/clinem/dgaf507
- Citations
- 1
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Fonds Wetenschappelijk Onderzoek
- Vlaamse regering