Understanding the Silent Threat: A Review to Neurodegenerative Disorders

Neurodegenerative disorders represent a global health challenge as they lead to the progressive deterioration of central and peripheral nervous system tissue structures, accompanied by declining neurological functions. This article provides extensive details about five leading neurodegenerative disorders, consisting of Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disease, and multiple sclerosis. The paper examines both prevalence and clinical indications, in addition to pathophysiological mechanisms, followed by diagnostic procedures and limitations in early detection. The increasing aging population requires health care systems to focus on these neurological conditions as a matter of global importance. Such a review incorporates contemporary findings and recent advanced concepts when dealing with devastating conditions.

Authors

Publication Details

Journal
Premier Journal of Neuroscience
Published
2025-09-08
DOI
https://doi.org/10.70389/pjn.100012
Primary Topic
Genetic Neurodegenerative Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Understanding the Silent Threat: A Review to Neurodegenerative Disorders

Amita Kajrolkar
Premier Journal of Neuroscience
Genetic Neurodegenerative Diseases
article

Understanding the Silent Threat: A Review to Neurodegenerative Disorders

Amita Kajrolkar
article en

Abstract

Neurodegenerative disorders represent a global health challenge as they lead to the progressive deterioration of central and peripheral nervous system tissue structures, accompanied by declining neurological functions. This article provides extensive details about five leading neurodegenerative disorders, consisting of Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disease, and multiple sclerosis. The paper examines both prevalence and clinical indications, in addition to pathophysiological mechanisms, followed by diagnostic procedures and limitations in early detection. The increasing aging population requires health care systems to focus on these neurological conditions as a matter of global importance. Such a review incorporates contemporary findings and recent advanced concepts when dealing with devastating conditions.

Premier Journal of Neuroscience
Openalex Percentile: Top 74%
Genetic Neurodegenerative Diseases
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