Analysis of the coronary artery calcium score for identifying coronary artery plaque in patients clinically referred for preventive screening with non-typical symptoms stratified by age and sex
The diagnostic accuracy of a CAC score of 0 improves with age. A CAC score of 0 does not reliably exclude coronary plaque in younger individuals, whereas its utility is greater in older adults.
Authors
- Jagat Narula (ORCID: https://orcid.org/0000-0002-0280-3996)
- H Rigby
- Amir Ahmadi (ORCID: https://orcid.org/0000-0002-5747-7112)
- Paul Knaapen
- Ruurt Jukema (ORCID: https://orcid.org/0000-0002-3212-2665)
- Ibrahim Danad (ORCID: https://orcid.org/0000-0002-3140-1320)
- Edgar Argulian (ORCID: https://orcid.org/0000-0003-2106-2668)
- Stephanie Sellers (ORCID: https://orcid.org/0000-0002-3539-5730)
- Philipp Blanke (ORCID: https://orcid.org/0009-0001-6128-6968)
- John King Khoo (ORCID: https://orcid.org/0000-0002-7226-8773)
- Bahram Pashaee (ORCID: https://orcid.org/0000-0002-9776-0318)
- Ashkan Parsa
- Jonathon Leipsic (ORCID: https://orcid.org/0009-0002-3892-9029)
- Anna Mueller (ORCID: https://orcid.org/0009-0004-3992-2966)
- Seunghwan Kim
- Abdulaziz A. Bin Zaid
- N. Nasibi
Institutions
- University of British Columbia (CA)
- Radboud University Nijmegen (NL)
- Thomas Jefferson University (US)
- Radboud University Medical Center (NL)
- Mount Sinai Hospital (US)
- St. Paul's Hospital (CA)
- Amsterdam University Medical Centers (NL)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Journal of cardiovascular computed tomography
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1016/j.jcct.2025.08.008
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Stichting de Drie Lichten