Influence of Glutathione S-transferase Mu 1 (GSTM1), Glutathione S-transferase Theta 1 (GSTT1), and N-acetyltransferase 2 (NAT2) Variants on Bladder Cancer Progression and Recurrence Rating: A Bosnian and Herzegovinian Case-Control Study
The GSTT1 T-- genotype was an independent predictor in the one- and five-year probabilities of both recurrence and progression of BC. GSTT1 rs17856199 may be a significant factor in the development of tumors and the course of disease in Bosnian and Herzegovinian BC patients.
Authors
- Izabela Uzar (ORCID: https://orcid.org/0000-0003-0159-5803)
- Grażyna Adler (ORCID: https://orcid.org/0000-0001-8792-553X)
- Osman Hadžiosmanović
- Benjamin Kulovac
- Almir Fajkić (ORCID: https://orcid.org/0000-0002-3722-9701)
- Amina Valjevac (ORCID: https://orcid.org/0000-0001-9229-1631)
Institutions
- University of Sarajevo (BA)
- Clinical Center University of Sarajevo (BA)
- Pomeranian Medical University (PL)
Publication Details
- Journal
- Cureus
- Published
- 2025-09-09
- DOI
- https://doi.org/10.7759/cureus.91948
- Primary Topic
- Glutathione Transferases and Polymorphisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NIH Clinical Center