Combination of immunotherapy-based systemic therapy and radiotherapy achieves durable response and favorable survival in recurrent head and neck cancer
This study presented promising survival and tumor control with durable response in recurrent HNSCC, supporting the use of radical RT as the first-line treatment in addition to ICI-based systemic therapy, in particular for patients with CPS ⩾ 20.
Authors
- Xuesong Chen (ORCID: https://orcid.org/0009-0001-6273-9850)
- Kai Wang (ORCID: https://orcid.org/0000-0003-4328-8799)
- Xiaohui He (ORCID: https://orcid.org/0000-0001-7121-1591)
- Sheng Yang (ORCID: https://orcid.org/0000-0002-0485-7728)
- Jingwei Luo (ORCID: https://orcid.org/0009-0004-4441-9927)
- Junlin Yi (ORCID: https://orcid.org/0000-0002-7083-0216)
- Lin Gui (ORCID: https://orcid.org/0000-0002-8054-9524)
- Gulidanna Shayan (ORCID: https://orcid.org/0009-0002-8612-5391)
- Runye Wu (ORCID: https://orcid.org/0009-0002-6959-5842)
- Yuchao Ma
- Ye Zhang (ORCID: https://orcid.org/0000-0002-3494-7206)
- Yuan Qu (ORCID: https://orcid.org/0000-0001-7297-0282)
- Xin Guo (ORCID: https://orcid.org/0009-0000-9335-0533)
- Xiaodong Huang (ORCID: https://orcid.org/0000-0003-3015-4986)
- Shengyu Zhou (ORCID: https://orcid.org/0000-0002-6254-2986)
- Jingbo Wang (ORCID: https://orcid.org/0000-0002-5233-5211)
- Jianghu Zhang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
Publication Details
- Journal
- Therapeutic Advances in Medical Oncology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1177/17588359251367358
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00