Outcome of ischemic mitral valve repair in patients with non-st elevation myocaridal infarction

Objective: Our study aimed to describe patient’s characteristics, as well as to evaluate the short-term and 12-month outcomes of patients with non-ST-elevation myocardial infarction having severe ischemic mitral regurgitation, who underwent coronary artery bypass grafting with or without concomitant mitral valve repair. Methods: A retrospective study was conducted on 39 patients who underwent CABG at Hanoi Heart Hospital from January 2020 to December 2022. Preoperative, intraoperative, postoperative, and 12-month follow-up data were collected and compared between two groups: those who underwent mitral valve repair and those who did not. Results: Among the 39 patients (13 islolated CABG, 26 CABG with mitral valve repair), the repair group had a higher preoperative mitral regurgitation severity compared to the non-repair group (2.9 ± 0.2 vs. 2.6 ± 0.2, p=0.006). Mitral regurgitation improved in both groups postoperatively; however, at 12 months, the repair group showed significantly lower mitralregurgitation (p=0.041). There were no significant differences between the two groups in left ventricular function, postoperative and 12-month mortality, or postoperative complications. However, the repair group had longer aortic cross-clamp times (p=0.002) and a trend toward more early complications. Conclusion: Mitral valve repair combined with coronary artery bypass grafting in the group of severe ischemic mitral valve regurgitation reduced the degree of valve regurgitation after 12 months compared with isolated coronary artery bypass grafting.