OP28 Comparison of efficacy transforaminal epidural injection of autologous platelet rich plasma vs triamcinolone in patient of lumbar disc herniation with radicular pain: a prosepective randomized control study

<h3>Background and Aims</h3> Low back pain is increasingly becoming a major health concern chronic low back pain with radicular symptoms is prevalent and debilitating conditions. Impact of lumbar radicular pain necessitates the exploration of safe and sustainable interventional strategies. Epidural transforaminal platelet rich plasma and triamcinolone represent two different modalities with distinct mechanism of actions. This study is aimed to compare the efficacy and safety of autologous platelet rich plasma versus Triamcinolone on lumbar radicular pain through fluoroscopy guided transforaminal epidural injection using VAS Scale. <h3>Methods</h3> A randomized controlled study was conducted as King George’s Medical University Lucknow including 60 patients having low back radicular pain. These patients were randomised to receive lumbar transforaminal epidural injections with either Triamcinolone (N=30) Group-S or Platelet rich Plasma (N=30) Group -P. Measurement were taken before treatment and 1 week, 2 week, 1 month, 3 month and 6 month using a visual analog scale <h3>Results</h3> In Group P the mean VAS decreased from a maximum of 7.86 at baseline to 3.55 at 3 month and then increased to 4.56 at 6 month and the result was statistically significant (p&lt;0.001).In Group S the mean VAS decreased from a maximum of 7.87 at the baseline to a minimum of 3.37 at the 1 month, and then increased to 6.10 at the 6 month. This change was statistically significant .Group -P patients has more pain relief than Group-S, there was statistically significant difference in the visual analog score between those treated with Triamcinolone and those with Platelets rich Plasma at 6 months(p&lt;0.001). <h3>Conclusions</h3> In this study, Triamcinolone and Platelet rich Plasma were shown to have beneficial effects on Lumbar radicular pain. The effect of Platelet rich plasma on pain relief has been found to be more and prolonged than with Triamcinolone.