An Unusual Presentation of Cutaneous Mucormycosis Mimicking Recalcitrant Dermatophytosis: A Case Report

We present the case of a 45-year-old woman who was initially diagnosed with and managed for recalcitrant tinea corporis and cruris.The patient had been treated with multiple courses of topical and systemic antifungal agents without clinical improvement.Upon further evaluation, mycological culture followed by molecular identification by sequencing of the internal transcribed spacer region confirmed Rhizopus stolonifer, a member of the Mucorales order, as the causative organism.The patient was subsequently treated with systemic posaconazole, leading to complete clinical resolution.This case underscores the importance of considering opportunistic molds like Mucorales in the differential diagnosis of chronic or treatment-resistant superficial fungal infections.It also highlights the critical role of advanced diagnostic modalities, including fungal culture and molecular methods, for accurate pathogen identification and appropriate antifungal therapy.

Authors

Publication Details

Journal
Turkish Journal of Dermatology
Published
2025-09-10
DOI
https://doi.org/10.4274/tjd.galenos.2025.18894
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

An Unusual Presentation of Cutaneous Mucormycosis Mimicking Recalcitrant Dermatophytosis: A Case Report

Selami Aykut Temiz, Sümeyye Aktaş, Selin Uğraklı, Hilal Sena Çiftci
Turkish Journal of Dermatology
Antifungal resistance and susceptibility
article

An Unusual Presentation of Cutaneous Mucormycosis Mimicking Recalcitrant Dermatophytosis: A Case Report

Selami Aykut Temiz, Sümeyye Aktaş, Selin Uğraklı, Hilal Sena Çiftci
article en

Abstract

We present the case of a 45-year-old woman who was initially diagnosed with and managed for recalcitrant tinea corporis and cruris.The patient had been treated with multiple courses of topical and systemic antifungal agents without clinical improvement.Upon further evaluation, mycological culture followed by molecular identification by sequencing of the internal transcribed spacer region confirmed Rhizopus stolonifer, a member of the Mucorales order, as the causative organism.The patient was subsequently treated with systemic posaconazole, leading to complete clinical resolution.This case underscores the importance of considering opportunistic molds like Mucorales in the differential diagnosis of chronic or treatment-resistant superficial fungal infections.It also highlights the critical role of advanced diagnostic modalities, including fungal culture and molecular methods, for accurate pathogen identification and appropriate antifungal therapy.

Turkish Journal of DermatologyVol. 19(3)
Openalex Percentile: Top 71%
Antifungal resistance and susceptibility
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