Investigation of the Antiparasitic Potential of Luteolin: In Vitro Activity and Comparison with Standard Therapeutics

Luteolin demonstrated potent antiprotozoal effects in vitro, with <i>L. tropica</i> being the most susceptible, followed by <i>A. castellanii</i> and <i>E. histolytica</i>. Notably, luteolin's anti-leishmanial activity was comparable to glucantime. In conclusion, luteolin demonstrates significant potential as a broad-spectrum antiparasitic agent, and comprehensive <i>in vivo</i> studies are recommended to further evaluate its therapeutic efficacy.