Multi-Criteria Decision Analysis of Biologics in Chronic Obstructive Pulmonary Disease
Biologics targeting T2 inflammation offer therapeutic promise in eosinophilic COPD when guided by biomarkers. Conversely, current biologics directed at non-T2 and alarmin pathways yield limited or inconsistent benefits, emphasizing the need for improved phenotyping and targeted intervention strategies in non-eosinophilic COPD.
Authors
- Luigino Calzetta (ORCID: https://orcid.org/0000-0003-0456-069X)
- Paola Rogliani (ORCID: https://orcid.org/0000-0001-7801-5040)
- Mario Cazzola (ORCID: https://orcid.org/0000-0003-4895-9707)
- Maria Gabriella Matera
Institutions
- University of Rome Tor Vergata (IT)
- University of Parma (IT)
- University of Campania "Luigi Vanvitelli" (IT)
Publication Details
- Journal
- International Journal of COPD
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/copd.s550144
- Citations
- 5
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 7.59