POST TUBERCULOSIS LUNG DISEASE IN AN ELDERLY PATIENT WITH PSEUDOMONAS INFECTION AND SUBCLINICAL HYPERTHYROIDISM: A CASE REPORT

Background: Post-tuberculosis lung disease (PTLD) is an underrecognized but increasingly prevalent sequela in TBendemic regions like South Asia. It encompasses structural pulmonary damage and systemic dysregulation, often complicated by opportunistic infections and age-related vulnerabilities. We report the case of a 64 Case Presentation: - year-old Indian female with prior microbiologically cured pulmonary tuberculosis, who presented with mucopurulent cough, orthopnea, and hemoptysis. Imaging revealed fibrotic bronchiectasis with tree-in-bud opacities, and sputum culture isolated Pseudomonas aeruginosa sensitive to meropenem. Concurrently, thyroid function tests showed suppressed TSH (0.007 mIU/L) with preserved FT4, and ultrasonography revealed a TIRADS 4 thyroid nodule. The patient also exhibited early frailty, diastolic dysfunction, and poorly controlled diabetes. She was managed Management: with IV meropenem, nebulized tobramycin, bronchodilators, and supportive care. Endocrine referral was advised for further evaluation of subclinical hyperthyroidism. Functional rehabilitation and discharge planning were coordinated via a multidisciplinary team. This case illustrates the co Conclusion: mplex interplay between PTLD, geriatric pharmacotherapy, endocrine dysfunction, and microbial resistance. It reinforces the need for structured post-TB surveillance and geriatric-integrated care models. The case contributes to evolving global understanding of PTLD as a multisystemic entity, particularly in aging diabetic populations in resource-constrained settings.

Authors

Institutions

Publication Details

Journal
PARIPEX INDIAN JOURNAL OF RESEARCH
Published
2025-08-15
DOI
https://doi.org/10.36106/paripex/3207849
Primary Topic
Medical Imaging and Pathology Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

POST TUBERCULOSIS LUNG DISEASE IN AN ELDERLY PATIENT WITH PSEUDOMONAS INFECTION AND SUBCLINICAL HYPERTHYROIDISM: A CASE REPORT

Vaishali Thakare, Dinesh Gupta, Maracy Mohammad Reza, Palakh Lukkad
PARIPEX INDIAN JOURNAL OF RESEARCH
Medical Imaging and Pathology Studies
article

POST TUBERCULOSIS LUNG DISEASE IN AN ELDERLY PATIENT WITH PSEUDOMONAS INFECTION AND SUBCLINICAL HYPERTHYROIDISM: A CASE REPORT

Vaishali Thakare, Dinesh Gupta, Maracy Mohammad Reza, Palakh Lukkad
article en

Abstract

Background: Post-tuberculosis lung disease (PTLD) is an underrecognized but increasingly prevalent sequela in TBendemic regions like South Asia. It encompasses structural pulmonary damage and systemic dysregulation, often complicated by opportunistic infections and age-related vulnerabilities. We report the case of a 64 Case Presentation: - year-old Indian female with prior microbiologically cured pulmonary tuberculosis, who presented with mucopurulent cough, orthopnea, and hemoptysis. Imaging revealed fibrotic bronchiectasis with tree-in-bud opacities, and sputum culture isolated Pseudomonas aeruginosa sensitive to meropenem. Concurrently, thyroid function tests showed suppressed TSH (0.007 mIU/L) with preserved FT4, and ultrasonography revealed a TIRADS 4 thyroid nodule. The patient also exhibited early frailty, diastolic dysfunction, and poorly controlled diabetes. She was managed Management: with IV meropenem, nebulized tobramycin, bronchodilators, and supportive care. Endocrine referral was advised for further evaluation of subclinical hyperthyroidism. Functional rehabilitation and discharge planning were coordinated via a multidisciplinary team. This case illustrates the co Conclusion: mplex interplay between PTLD, geriatric pharmacotherapy, endocrine dysfunction, and microbial resistance. It reinforces the need for structured post-TB surveillance and geriatric-integrated care models. The case contributes to evolving global understanding of PTLD as a multisystemic entity, particularly in aging diabetic populations in resource-constrained settings.

PARIPEX INDIAN JOURNAL OF RESEARCH
Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN), D.Y. Patil University (IN), Dr D Y Patil Dental College & Hospital (IN)
Openalex Percentile: Top 65%
Medical Imaging and Pathology Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

POST TUBERCULOSIS LUNG DISEASE IN AN ELDERLY PATIENT WITH PSEUDOMONAS INFECTION AND SUBCLINICAL HYPERTHYROIDISM: A CASE REPORT — Vaishali Thakare, Dinesh Gupta, et al. · PARIPEX INDIAN JOURNAL OF RESEARCH (2025) | TGRS Research Map | TGRS