Qiangxin bushen decoction attenuates cardiorenal syndrome type II via AMPK/FOXO1-mediated ferroptosis pathway: A multi-omics and experimental study
This study reveals that QBQ exerts its cardiorenal protection for CRS2 through AMPK/FOXO1-dependent ferroptosis inhibition with contemporary multi-omics research tools.
Authors
- Sijie Yao (ORCID: https://orcid.org/0000-0003-4228-0832)
- Hui Zhang (ORCID: https://orcid.org/0000-0001-8749-5285)
- Xinyue Ding (ORCID: https://orcid.org/0000-0003-1375-9473)
- Junfeng Qian
- Yali Sun (ORCID: https://orcid.org/0000-0002-1471-4122)
- Shuo Han (ORCID: https://orcid.org/0000-0001-8982-8514)
- Xuan Zhao (ORCID: https://orcid.org/0000-0002-5650-0747)
- Lina Xing (ORCID: https://orcid.org/0000-0001-7746-5445)
- Zongjun Liu (ORCID: https://orcid.org/0000-0003-1845-525X)
Institutions
- Shanghai Ninth People's Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Central Hospital of Putuo District (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-09-10
- DOI
- https://doi.org/10.1016/j.phymed.2025.157247
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56