Presence of Vaccine-Induced Antibodies Against Leptospira spp. Complicates the Diagnosis of Leptospirosis by the Microscopic Agglutination Test
These findings suggest that high levels of antibody titres against <i>Leptospira</i> spp. occur frequently and cross-reactivity against non-vaccine serovars is likely. The detection of vaccine-induced antibodies can therefore complicate the diagnosis of leptospirosis.
Authors
- Katrin Hartmann (ORCID: https://orcid.org/0000-0002-5256-863X)
- Yury Zablotski (ORCID: https://orcid.org/0000-0001-6928-4089)
- Ahmed A. Ahmed (ORCID: https://orcid.org/0000-0002-6169-5323)
- Katharina Gesa Schmitt
- Hans van der Linden (ORCID: https://orcid.org/0009-0006-8656-5839)
- Michèle Bergmann (ORCID: https://orcid.org/0000-0002-8856-3849)
- Reinhard Konrad Straubinger (ORCID: https://orcid.org/0000-0001-8382-7182)
Institutions
- Netherlands Institute for Neuroscience (NL)
- University of Veterinary Medicine Vienna (AT)
- Institute of Bioinformatics and Systems Biology (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Vaccines
- Published
- 2025-09-08
- DOI
- https://doi.org/10.3390/vaccines13090956
- Citations
- 1
- Primary Topic
- Leptospirosis research and findings
- Type
- article
- Field-Weighted Citation Impact
- 2.05