Biliary Tract Cancers, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology
The NCCN Guidelines for Biliary Tract Cancers (BTCs) provide recommendations for the evaluation and comprehensive care of patients with gallbladder cancer, intrahepatic cholangiocarcinoma, and extrahepatic cholangiocarcinoma. The multidisciplinary panel of experts is convened at least once annually to review requests from internal and external entities as well as to evaluate new data on current and emerging therapies. This manuscript focuses on the adjuvant chemotherapy and chemoradiation treatment options for BTCs as well as the systemic treatment recommendations for patients with advanced BTCs.
Authors
- Matthew H. Levine (ORCID: https://orcid.org/0000-0003-4525-5827)
- Michael I. D’Angelica (ORCID: https://orcid.org/0000-0002-3731-0534)
- Stacey Stein (ORCID: https://orcid.org/0000-0001-8970-9144)
- Adam M. Burgoyne (ORCID: https://orcid.org/0000-0002-4351-9940)
- Joseph W. Franses (ORCID: https://orcid.org/0000-0002-2517-4950)
- Daniel B. Brown (ORCID: https://orcid.org/0000-0003-0533-2883)
- Manisha Palta (ORCID: https://orcid.org/0000-0002-9085-9075)
- Robin Kate Kelley (ORCID: https://orcid.org/0000-0002-1984-2430)
- Laleh Golkar Melstrom (ORCID: https://orcid.org/0000-0001-6279-7981)
- Robert A. Anders (ORCID: https://orcid.org/0000-0002-2363-9072)
- Al B. Benson (ORCID: https://orcid.org/0000-0001-5485-7227)
- Anita Turk (ORCID: https://orcid.org/0000-0002-4159-5376)
- Sean M. Ronnekleiv‐Kelly (ORCID: https://orcid.org/0000-0001-6664-996X)
- Alan P. Venook (ORCID: https://orcid.org/0000-0001-9749-6548)
- Darren R. Cullinan (ORCID: https://orcid.org/0000-0002-9161-212X)
- Melinda Bachini (ORCID: https://orcid.org/0000-0001-6850-2929)
- Thomas A. Abrams (ORCID: https://orcid.org/0000-0003-3101-1573)
- Cindy Hochstetler
- Renuka Iyer (ORCID: https://orcid.org/0000-0003-3643-8621)
- Jordan M. Cloyd (ORCID: https://orcid.org/0000-0002-2373-8433)
- Lydia Aye
- Steven S. Raman (ORCID: https://orcid.org/0000-0003-0499-1676)
- Ryan Schonfeld
- Sajid Khan (ORCID: https://orcid.org/0000-0001-9897-6025)
- Motoyo Yano (ORCID: https://orcid.org/0000-0002-4837-1906)
- Kevin L. Stephans (ORCID: https://orcid.org/0000-0002-5554-8474)
- Vaibhav Sahai (ORCID: https://orcid.org/0000-0003-1892-1548)
- Chandrakanth Are (ORCID: https://orcid.org/0000-0001-7822-8898)
- Mehmet Akce (ORCID: https://orcid.org/0000-0003-4747-7722)
- Ken Zhao
- Kannan Thanikachalam (ORCID: https://orcid.org/0000-0001-5379-8966)
- Lawrence J. Jennings (ORCID: https://orcid.org/0000-0001-8669-7774)
- Adam C. Yopp (ORCID: https://orcid.org/0000-0002-5887-5315)
- Jean‐Nicolas Vauthey (ORCID: https://orcid.org/0000-0003-4921-5427)
- Evan S. Glazer (ORCID: https://orcid.org/0000-0002-5796-0542)
- Daniel A. Anaya (ORCID: https://orcid.org/0000-0002-6569-3931)
- David C. Binder
- Marshall S. Baker
- Jason Castellanos (ORCID: https://orcid.org/0000-0003-0771-3727)
- William P. Harris
- Aijaz Ahmed
Institutions
- Fox Chase Cancer Center (US)
- Roswell Park Comprehensive Cancer Center (US)
- Barnes-Jewish Hospital (US)
- City Of Hope National Medical Center (US)
- St. Jude Children's Research Hospital (US)
- Cleveland Clinic (US)
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Tennessee Health Science Center (US)
- Breast Cancer Research Foundation (US)
- University of Utah (US)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- UC San Diego Health System (US)
- Huntsman Cancer Institute (US)
- Cancer Institute (WIA) (IN)
- Susan Thompson Buffett Foundation (US)
- WinnMed (US)
- Yale Cancer Center (US)
- Moffitt Cancer Center (US)
- Fred Hutch Cancer Center (US)
- Southwestern Medical Center (US)
- Jewish Hospital (US)
- University of Wisconsin Carbone Cancer Center (US)
- Sidney Kimmel Cancer Center (US)
- University Hospitals Seidman Cancer Center (US)
- Duke Medical Center (US)
- University of Colorado Cancer Center (US)
- Cholangiocarcinoma Foundation (US)
- Dana-Farber Brigham Cancer Center (US)
- Smilow Cancer Hospital (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center
- Moores Cancer Center
- University of Chicago Medicine Comprehensive Cancer Center
- UCLA Jonsson Comprehensive Cancer Center
- Vanderbilt-Ingram Cancer Center
- Stanford Cancer Institute
- Duke Cancer Institute
- Fred and Pamela Buffett Cancer Center
- UC Davis Comprehensive Cancer Center
- Harold C. Simmons Comprehensive Cancer Center
- O'Neal Comprehensive Cancer Center
- National Comprehensive Cancer Network
- Indiana University (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of the National Comprehensive Cancer Network
- Published
- 2025-09-01
- DOI
- https://doi.org/10.6004/jnccn.2025.0042
- Citations
- 11
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 22.07