Advanced Graph–Physics Hybrid Framework (AGPHF) for Holistic Integration of AI-Driven Graph- and Physics- Methodologies to Promote Resilient Wastewater Management in Dynamic Real-World Conditions
Wastewater treatment is evolving rapidly with the advent of advanced deep-learning AI, graph-based, and physics-informed approaches. This study integrates graph neural networks, physics-informed neural networks, and multi-agent reinforcement learning within a hybrid digital-twin framework, evaluated on multi-scale real-world datasets. The developed models achieved over 90% dissolved organic carbon removal and reduced aeration energy by up to 22% while maintaining process stability. The results demonstrate that graph–physics synergies not only boost operational efficiency but also reveal critical trade-offs between energy savings and hydraulic performance. Our findings establish a new benchmark for resilient, low-carbon wastewater treatment, highlighting the transformative role of data-driven system design.
Authors
- George A. Papakostas (ORCID: https://orcid.org/0000-0001-5545-1499)
- Zongliang Yue (ORCID: https://orcid.org/0000-0001-8290-123X)
- Εleni Vrochidou (ORCID: https://orcid.org/0000-0002-0148-8592)
- Clark Xu (ORCID: https://orcid.org/0000-0002-2384-4244)
- Vasileios Alevizos (ORCID: https://orcid.org/0000-0002-3651-2134)
- George E. Marnellos (ORCID: https://orcid.org/0000-0003-4174-4455)
- Mousa Mustafa
- Sabrina Edralin (ORCID: https://orcid.org/0009-0003-6225-6351)
- Nikitas Gerolimos (ORCID: https://orcid.org/0009-0009-9085-0837)
Institutions
- Mayo Clinic (US)
- Democritus University of Thrace (GR)
- University of Illinois Urbana-Champaign (US)
- Harvard University Press (US)
- Karolinska Institutet (SE)
- Cambridge Scientific (United States) (US)
- Technische Universität Berlin (DE)
- Auburn University (US)
- University of the Aegean (GR)
Publication Details
- Journal
- Applied Sciences
- Published
- 2025-09-10
- DOI
- https://doi.org/10.3390/app15189905
- Citations
- 6
- Primary Topic
- Smart Grid Security and Resilience
- Type
- article
- Field-Weighted Citation Impact
- 7.29