Indirect bilirubin is inversely associated with diabetic retinopathy risk and is a potential predictive biomarker
These findings suggest that IBIL could be a valuable biomarker for predicting DR risk, offering a noninvasive, cost-effective, and readily available clinical tool for the early identification of high-risk patients. Future multicenter and longitudinal studies are warranted to validate these findings and further explore the biological mechanisms underlying the protective role of IBIL in DR.
Authors
- Xiaoying Lin (ORCID: https://orcid.org/0009-0004-9084-641X)
- Qian Liang (ORCID: https://orcid.org/0000-0002-8348-0833)
- Mingqian He (ORCID: https://orcid.org/0009-0003-1239-5740)
- Jing Sui (Beijing Normal University), my correct affiliation is beijing normal university, not Qingdao University of Science and Technology, please correct the current affiliation. Thank you (ORCID: https://orcid.org/0000-0001-6837-5966)
- Hui Guo (ORCID: https://orcid.org/0000-0003-3211-4806)
- Meng Li (ORCID: https://orcid.org/0000-0002-1749-9253)
- Bingyin Shi (ORCID: https://orcid.org/0000-0003-4627-5707)
- Qiang Wei (ORCID: https://orcid.org/0000-0003-0535-8506)
- Meng-Meng Liu (ORCID: https://orcid.org/0009-0006-4104-4335)
- Yixuan Zheng (ORCID: https://orcid.org/0009-0008-6367-6901)
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- First Hospital of Xi'an (CN)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2025-09-10
- DOI
- https://doi.org/10.4239/wjd.v16.i9.110590
- Citations
- 2
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 1.61