CLINICAL PROFILE AND PRECIPITATING FACTORS OF DIABETIC KETOACIDOSIS IN ADULTS: A RETROSPECTIVE OBSERVATIONAL STUDY

Background: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. Understanding the clinical profile, precipitating factors, and outcomes can inform prevention strategies and optimize care. Aim: To describe the clinical profile, precipitating factors, and short-term outcomes of adult patients admitted with DKA at a tertiary care center.Department of general medicine,SRG Hospital & Jhalawar medical collage,Jhalawar Methods:We conducted a retrospective observational study of consecutive adult patients (≥18 years) admitted with DKA between July 2024 to June 2025. Data included demographics, type of diabetes, precipitating factors, biochemical parameters at admission,length of stay, and in-hospital outcome.Descriptive statistics were used.Results:A total of 30 patients were included (mean age 45.3 years;males 66.7%).The most common precipitating factor was infection (40.0%),followed by missed insulin and new-onset diabetes. Mean random blood glucose was 489 mg/dL, mean pH 7.17, and mean bicarbonate 10.8 mmol/L.Median hospital stay was 7.0 days.In-hospital mortality was 13.3%.Conclusion:In this singlecenter cohort, infection was the leading precipitant for DKA, and overall mortality was low.Targeted patient education and early infection management may reduce recurrence and improve outcomes.

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Journal
PARIPEX INDIAN JOURNAL OF RESEARCH
Published
2025-08-15
DOI
https://doi.org/10.36106/paripex/6510035
Primary Topic
Diabetes and associated disorders
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article
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article

CLINICAL PROFILE AND PRECIPITATING FACTORS OF DIABETIC KETOACIDOSIS IN ADULTS: A RETROSPECTIVE OBSERVATIONAL STUDY

C Datta, Ragitha Ramesh, Bhagwan Prasad Meena
PARIPEX INDIAN JOURNAL OF RESEARCH
Diabetes and associated disorders
article

CLINICAL PROFILE AND PRECIPITATING FACTORS OF DIABETIC KETOACIDOSIS IN ADULTS: A RETROSPECTIVE OBSERVATIONAL STUDY

C Datta, Ragitha Ramesh, Bhagwan Prasad Meena
article en

Abstract

Background: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. Understanding the clinical profile, precipitating factors, and outcomes can inform prevention strategies and optimize care. Aim: To describe the clinical profile, precipitating factors, and short-term outcomes of adult patients admitted with DKA at a tertiary care center.Department of general medicine,SRG Hospital & Jhalawar medical collage,Jhalawar Methods:We conducted a retrospective observational study of consecutive adult patients (≥18 years) admitted with DKA between July 2024 to June 2025. Data included demographics, type of diabetes, precipitating factors, biochemical parameters at admission,length of stay, and in-hospital outcome.Descriptive statistics were used.Results:A total of 30 patients were included (mean age 45.3 years;males 66.7%).The most common precipitating factor was infection (40.0%),followed by missed insulin and new-onset diabetes. Mean random blood glucose was 489 mg/dL, mean pH 7.17, and mean bicarbonate 10.8 mmol/L.Median hospital stay was 7.0 days.In-hospital mortality was 13.3%.Conclusion:In this singlecenter cohort, infection was the leading precipitant for DKA, and overall mortality was low.Targeted patient education and early infection management may reduce recurrence and improve outcomes.

PARIPEX INDIAN JOURNAL OF RESEARCH
Jawaharlal Nehru Medical College (IN)
Openalex Percentile: Top 74%
Diabetes and associated disorders
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