Impact of D3 lymph node dissection extent on postoperative bowel function and nutritional status in right-sided colon cancer: a prospective randomized controlled trial
Extending D3 lymphadenectomy to the SMA increases lymph node yield but is associated with a higher incidence of postoperative diarrhea and chylous leakage, without clear short-term oncologic benefit. These findings underscore the importance of balancing oncologic thoroughness with functional recovery and may inform more individualized, patient-centered surgical planning through shared decision-making.
Authors
- Guodong Lian (ORCID: https://orcid.org/0000-0002-8459-0057)
- Zhou Shang
- Baolin Zhang (ORCID: https://orcid.org/0000-0002-2238-3351)
- Yuezhi Chen (ORCID: https://orcid.org/0000-0003-4226-4939)
- Xinxiu Zhou
- Leping Li (ORCID: https://orcid.org/0000-0003-2329-6791)
- Changqing Jing (ORCID: https://orcid.org/0000-0002-3933-3721)
- Jiyuan Liu (ORCID: https://orcid.org/0000-0002-0621-9164)
- Feng Tian (ORCID: https://orcid.org/0000-0001-8570-1217)
- Mingshuai Bai
Institutions
- Second Hospital of Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1097/js9.0000000000003485
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00