Feasibility of a reduced gadolinium dose protocol for MRI-guided radiotherapy in glioblastoma
Reduced-dose GBCA-protocols are feasible. Full-dose contrast is recommended at key fractions (e.g. baseline and mid-treatment) and for small tumours, with half-dose imaging reserved for selected intervals or larger tumours. This hybrid approach may balance safety and imaging precision in adaptive MRIgRT.
Authors
- Bahar Çelik
- Anne Louise Højmark Bisgaard (ORCID: https://orcid.org/0000-0002-5402-0045)
- Tine Schytte (ORCID: https://orcid.org/0000-0002-6705-1561)
- Faisal Mahmood (ORCID: https://orcid.org/0000-0002-7270-7967)
- Rasmus Lübeck Christiansen (ORCID: https://orcid.org/0000-0003-3254-5075)
- Rikke Hedegaard Dahlrot (ORCID: https://orcid.org/0000-0003-1538-4361)
- Uffe Bernchou (ORCID: https://orcid.org/0000-0002-5309-2696)
- A. Bertelsen (ORCID: https://orcid.org/0000-0003-0022-0786)
- Elisabeth Kildegaard
- Frederik Severin Gråe Harboe
Institutions
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
Publication Details
- Journal
- Acta Oncologica
- Published
- 2025-09-10
- DOI
- https://doi.org/10.2340/1651-226x.2025.44022
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Odense Universitetshospital