Evaluation of Calcium Hydroxide, Triple Antibiotic Paste, Mineral Trioxide Aggregate and Biodentine as Pulp Capping Agents in Deep Carious Teeth

INTRODUCTION Deep caries Management (DCM) with a reliable biomaterial is considered an alternative to Root Canal Treatment (RCT) provided the pulp is vital. Calcium Hydroxide (CH) and Mineral Trioxide Aggregate (MTA) are relatively more popular as pulp capping agents. Triple Antibiotic Paste (TAP) has been proposed for lesion sterilization and tissue repair (LSTR). Biodentine is relatively new biomaterial currently explored for vital pulp therapy. MATERIAL AND METHODS A total of 100 cases confirmed eligible for pulp capping were randomly assigned to either CH, TAP, MTA or Biodentine group (25 teeth per group). The allocated pulp capping agent was applied followed by Glass Ionomer Cement. Permanent restoration was done with composite at 3rd week. Clinical and radiographic evaluations were performed at 3 weeks, 3 months, 6 months and 1 year. Teeth presenting with severe pain or no response to pulp sensibility tests or demonstrating periapical changes in the radiograph were considered failures. RESULTS Biodentine and MTA had 22 (31.9%) successful cases each. CH had 13 (18.8%) successful cases and TAP had 12 (17.4%). There was statistically significant difference in the pain score between Biodentine and CH, between Biodentine and TAP at 6 months. There was statistically significant difference in the vitality of the teeth for the pulp capping materials at 3 weeks while no significant difference in the radiographic findings. CONCLUSION Biodentine and MTA showed better outcome than CH and TAP based on subjective symptoms, pulp sensibility tests and radiographic findings. Thus, Biodentine and MTA can be used as replacement for CH and TAP as pulp capping material.

Authors

Institutions

Publication Details

Journal
Journal of Universal College of Medical Sciences
Published
2025-09-10
DOI
https://doi.org/10.3126/jucms.v13i02.83851
Primary Topic
Endodontics and Root Canal Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Evaluation of Calcium Hydroxide, Triple Antibiotic Paste, Mineral Trioxide Aggregate and Biodentine as Pulp Capping Agents in Deep Carious Teeth

Manisha Nepal, Vanita Gautam, Snigdha Shubham, Sujan Thapa et al.
Journal of Universal College of Medical Sciences
Endodontics and Root Canal Treatments
article

Evaluation of Calcium Hydroxide, Triple Antibiotic Paste, Mineral Trioxide Aggregate and Biodentine as Pulp Capping Agents in Deep Carious Teeth

Manisha Nepal, Vanita Gautam, Snigdha Shubham, Sujan Thapa, Rupam Tripathi
article en

Abstract

INTRODUCTION Deep caries Management (DCM) with a reliable biomaterial is considered an alternative to Root Canal Treatment (RCT) provided the pulp is vital. Calcium Hydroxide (CH) and Mineral Trioxide Aggregate (MTA) are relatively more popular as pulp capping agents. Triple Antibiotic Paste (TAP) has been proposed for lesion sterilization and tissue repair (LSTR). Biodentine is relatively new biomaterial currently explored for vital pulp therapy. MATERIAL AND METHODS A total of 100 cases confirmed eligible for pulp capping were randomly assigned to either CH, TAP, MTA or Biodentine group (25 teeth per group). The allocated pulp capping agent was applied followed by Glass Ionomer Cement. Permanent restoration was done with composite at 3rd week. Clinical and radiographic evaluations were performed at 3 weeks, 3 months, 6 months and 1 year. Teeth presenting with severe pain or no response to pulp sensibility tests or demonstrating periapical changes in the radiograph were considered failures. RESULTS Biodentine and MTA had 22 (31.9%) successful cases each. CH had 13 (18.8%) successful cases and TAP had 12 (17.4%). There was statistically significant difference in the pain score between Biodentine and CH, between Biodentine and TAP at 6 months. There was statistically significant difference in the vitality of the teeth for the pulp capping materials at 3 weeks while no significant difference in the radiographic findings. CONCLUSION Biodentine and MTA showed better outcome than CH and TAP based on subjective symptoms, pulp sensibility tests and radiographic findings. Thus, Biodentine and MTA can be used as replacement for CH and TAP as pulp capping material.

Journal of Universal College of Medical SciencesVol. 13(02)
Patan Academy of Health Sciences (NP), Pokhara University (NP), College of Medical Sciences (NP), Universal College of Medical Sciences, Kathmandu University (NP)
Openalex Percentile: Top 66%
Endodontics and Root Canal Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.