Numerical analysis of the resolution limit in microparticle-assisted super-resolution microscopy

Visualization in the virtual image formed by dielectric microparticles has been shown to enable the distinction of objects that remain indistinguishable under direct observation. We perform the resolution analysis based on a full two-dimensional simulation in the TE mode of optical image formation, taking into account the diffraction of partially coherent light on the microparticle and the objects under study. The oscillating nature of optical resolution is demonstrated depending on the size of the microparticle. The presence of strong resonances is observed in both transmission and reflection modes. It is shown that as the size of the object decreases, the optical resolution tends to the classical limit. An analytical estimate for the resolution criterion is presented.

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Journal
Journal of the Optical Society of America A
Published
2025-09-10
DOI
https://doi.org/10.1364/josaa.573559
Primary Topic
Advanced Fluorescence Microscopy Techniques
Type
article
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article

Numerical analysis of the resolution limit in microparticle-assisted super-resolution microscopy

Boris Luk’yanchuk, Andrey A. Fedyanin, A. R. Bekirov, Zengbo Wang et al.
Journal of the Optical Society of America A
Advanced Fluorescence Microscopy Techniques
article

Numerical analysis of the resolution limit in microparticle-assisted super-resolution microscopy

Boris Luk’yanchuk, Andrey A. Fedyanin, A. R. Bekirov, Zengbo Wang, Nina A. Lystseva
article en

Abstract

Visualization in the virtual image formed by dielectric microparticles has been shown to enable the distinction of objects that remain indistinguishable under direct observation. We perform the resolution analysis based on a full two-dimensional simulation in the TE mode of optical image formation, taking into account the diffraction of partially coherent light on the microparticle and the objects under study. The oscillating nature of optical resolution is demonstrated depending on the size of the microparticle. The presence of strong resonances is observed in both transmission and reflection modes. It is shown that as the size of the object decreases, the optical resolution tends to the classical limit. An analytical estimate for the resolution criterion is presented.

Journal of the Optical Society of America AVol. 42(10)
Bangor University (GB)
Openalex Percentile: Top 83%
Advanced Fluorescence Microscopy Techniques
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Numerical analysis of the resolution limit in microparticle-assisted super-resolution microscopy — Boris Luk’yanchuk, Andrey A. Fedyanin, et al. · Journal of the Optical Society of America A (2025) | TGRS Research Map | TGRS