Gender-Specific Associations of CYP4F2 (rs1558139) Gene Polymorphism and Serum Levels in Early and Exudative Age-Related Macular Degeneration
The <i>CYP4F2</i> rs1558139 polymorphism shows gender-specific associations with AMD. The A allele is less frequent only in females with early AMD, while the AA genotype is more common in women with exudative AMD. A higher serum CYP4F2 level may contribute to the development of AMD.
Authors
- Rasa Liutkevičienė (ORCID: https://orcid.org/0000-0001-5395-923X)
- Alvita Vilkevičiūtė (ORCID: https://orcid.org/0000-0002-0427-5568)
- Loresa Kriauciuniene
- Raimonda Piškinienė
- Rasa Čiumbaraitė
- Ho Hin
- Enrika Pileckaitė
Institutions
- Lithuanian University of Health Sciences (LT)
Publication Details
- Journal
- Cureus
- Published
- 2025-09-10
- DOI
- https://doi.org/10.7759/cureus.91988
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00