Treatment completion and challenges in rolling out 12-dose weekly rifapentine plus isoniazid to prevent tuberculosis among people living with HIV and pediatric household contacts in Brazil
The 3HP regimen was successfully introduced, had high treatment completion rates, and was well tolerated. Widespread use of 3HP for TPT may accelerate tuberculosis elimination in Brazil.
Authors
- Solange Cavalcante (ORCID: https://orcid.org/0000-0002-4154-7016)
- Jamile G. de Oliveira
- Valéria Saraceni (ORCID: https://orcid.org/0000-0001-7360-6490)
- Violet Chihota (ORCID: https://orcid.org/0000-0003-1444-9266)
- Gavin Churchyard (ORCID: https://orcid.org/0000-0002-4269-3699)
- Renata Spener-Gomes (ORCID: https://orcid.org/0000-0003-3913-9985)
- Isadora Salles (ORCID: https://orcid.org/0000-0003-2670-8069)
- Alexandra B. Souza (ORCID: https://orcid.org/0000-0002-0849-8398)
- Betina Durovni (ORCID: https://orcid.org/0000-0002-5555-8015)
- Marcelo Cordeiro‐Santos (ORCID: https://orcid.org/0000-0002-7140-7145)
- Richard E. Chaisson (ORCID: https://orcid.org/0000-0003-4710-925X)
- Makaita Gombe
- Silvia Cohn
- Solange Dourado de Andrade
- J Weiser
Institutions
- Secretaria Municipal de Educação de São Paulo (BR)
- Secretaria Municipal de Saúde (BR)
Publication Details
- Journal
- Jornal Brasileiro de Pneumologia
- Published
- 2025-08-29
- DOI
- https://doi.org/10.36416/1806-3756/e20250125
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00