Grades 3 and 4 adult-type diffuse gliomas: epidemiology and radiomics in Guanajuato, Mexico

Objective:The objective of the study is to report epidemiological characteristics and prognostic factors of patients with adult-type gliomas treated in the neurosurgery department of the National Medical Center of Bajo, as well as to evaluate, for the 1 st time in Mexican patients, surface regularity (SR).Methods: Epidemiological and clinical features were statistically compared with international references.Survival was estimated using the Kaplan-Meier method.Kaplan-Meier curves were compared with the log-rank test.SR was obtained by segmenting magnetic resonance imaging.Results: Median age of patients with glioblastomas was less than that of patients in the United States (p = 0.021).The administration of radiotherapy (RT) and temozolomide (TMZ) prolonged survival (median gain of 35 months).Median SR was 0.6006 and was close to being statistically lower than the value reported in a large cohort (p = 0.09).Conclusions: Glioblastomas were diagnosed at younger ages and appeared to be more aggressive.The administration of RT and TMZ prolonged substantially survival.