EXTRACTION AND ISOLATION OF BIOACTIVE COMPOUNDS FROM CORAL JUNCEELLA DELICATA (GRASSHOFF, 1999) FROM WEST COAST OF MUMBAI
Objective: To isolate the bioactive compounds from coral Junceella delicata (Grasshoff, 1999) collected from West coast of Mumbai. Methods: The coral J. delicata was collected from Patwadi Village, Madh Island, Malad West Mumbai-400061, Maharashtra, India, during the low tide. The sample was grinded with blender and then macerated by adding an equal volume of MeOH: DCM (1:1). The aliquot was concentrated in a rotary vacuum evaporator at 45 °C. The resultant compound was subjected to Millipore filter system and finally dried in vacuum desiccator. The sample was further subjected for TLC and pure compounds were processed for GC-MS and FTIR for structural determinations. Results: The distinct and well-separated compounds were processed for GC-MS and FTIR for their structural elucidation. These compounds are (Ethyl aminomethyl formimidate); (Gly-Gly); (2-(2-Pyridyl)-4 methylthiazole-5-carboxylic acid); (7-Methoxy-2-methylquinolin-4-ol); (Fraxidin); (2-methyl-3-trans-propenylpyrazine); (3-tert-Butylpyridine); (Acetaldehyde benzyl ethyl acetal); (α-Methylcinnamic acid); (4-Ethoxycoumarin); (3-Hydroxycoumarin); (2, 4, 7, 9-Tetramethyl-5-decyne-4, 7-diol); (2,2-Bis(3-allyl-4-hydroxyphenyl) propane); (Phenyltriethylammonium cation); (Dodecanedioic acid). These compounds showed biomedical properties. Conclusion: The isolated bioactive compounds may be used for pharmaceutical and therapeutic applications. Further studies, including molecular-level research, are necessary to confirm their mechanisms of action and clinical relevance. Additionally, safety and efficacy assessments are crucial to support the development of new pharmaceutical products aimed at improving human health.
Authors
- G. V. Zodape (ORCID: https://orcid.org/0000-0003-1278-6365)
- Meenakshi Prakash Borate
Institutions
- G.S. Science, Arts And Commerce College (IN)
Publication Details
- Journal
- International Journal of Pharmacy and Pharmaceutical Sciences
- Published
- 2025-09-01
- DOI
- https://doi.org/10.22159/ijpps.2025v17i9.54605
- Citations
- 1
- Primary Topic
- Marine Sponges and Natural Products
- Type
- article
- Field-Weighted Citation Impact
- 1.23
Funders
- Indian Institute of Technology Madras
- Indian Institute of Technology Bombay