Alterations in serum and intestinal ACE2 in Inflammatory Bowel Disease and the impact of inflammation
We observe significant increases in colonic ACE2 expression in IBD, especially with active colitis. Corticosteroids further modify the observed imbalance between tissue and serum ACE2 levels.
Authors
- Seán Martin (ORCID: https://orcid.org/0000-0001-7600-0291)
- Hugh Mulcahy (ORCID: https://orcid.org/0000-0002-7087-6177)
- Glen A. Doherty (ORCID: https://orcid.org/0000-0003-4384-5049)
- Catherine Rowan (ORCID: https://orcid.org/0000-0002-2403-7436)
- Ciara Egan
- Sarah J. Kierans (ORCID: https://orcid.org/0000-0003-0691-8237)
- Margaret Walshe (ORCID: https://orcid.org/0000-0002-8696-354X)
- Miriam Tosetto
- Moritz J. Strowitzki (ORCID: https://orcid.org/0000-0001-6967-9283)
- Cormac T. Taylor (ORCID: https://orcid.org/0000-0002-0946-1247)
- Juliette Sheridan (ORCID: https://orcid.org/0000-0002-0022-3015)
- Elizabeth Ryan (ORCID: https://orcid.org/0000-0001-8680-3741)
- Maura B. Cotter (ORCID: https://orcid.org/0000-0003-1720-2840)
- Garret Cullen
- Fiona Jones
Institutions
- University College Dublin (IE)
- University of Limerick (IE)
- St. Vincent's University Hospital (IE)
Publication Details
- Journal
- Frontiers in Gastroenterology
- Published
- 2025-09-10
- DOI
- https://doi.org/10.3389/fgstr.2025.1590646
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00