CCDC58 drives lung adenocarcinoma progression via the PI3K/AKT signaling pathway
Above all, this study reveals that CCDC58 plays multiple pro-tumorigenic roles in the progression of LUAD. These results enhance the understanding of LUAD pathogenesis and highlight CCDC58 as a potential therapeutic target and prognostic biomarker.
Authors
- Jun Yang (ORCID: https://orcid.org/0000-0002-9401-3528)
- Weixing Dai (ORCID: https://orcid.org/0000-0002-5395-8568)
- Wenming Yang (ORCID: https://orcid.org/0000-0001-8509-2140)
- Xin Dang (ORCID: https://orcid.org/0000-0002-3372-3825)
- Jiang Li (ORCID: https://orcid.org/0000-0001-5596-9159)
- Hang Chen (ORCID: https://orcid.org/0000-0002-6356-3930)
- Xue Li (ORCID: https://orcid.org/0000-0001-9793-8844)
- Guibin Zhang (ORCID: https://orcid.org/0000-0001-7759-5610)
- Bi Ren
Institutions
- North Sichuan Medical University (CN)
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-10
- DOI
- https://doi.org/10.3389/fonc.2025.1619123
- Primary Topic
- Caveolin-1 and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00