Antimicrobial effect of benzbromarone combined with colistin against multidrug-resistant bacteria

This study revealed that benzbromarone enhanced the antibacterial activity of colistin against COPD-associated drug-resistant pathogens, exhibiting a significant synergistic effect while effectively reducing the required colistin dosage. These findings provide a promising alternative approach for antimicrobial therapy in drug-resistant COPD infections and contribute to the exploration of new antibacterial applications for non-antibiotic drugs.