Analyzing the impact of human leukocyte antigen mismatch on the incidence of prostate cancer and the advantage of T cell therapy in patients after kidney transplantation based on the United Network for Organ Sharing database

From the perspective of prostate cancer occurrence after transplantation, the use of T cell therapy is of great significance. HLA mismatch ≥ 3 was a risk factor of prostate cancer after KT. HLA-A and HLA-B 2-mismatch were risk factors of prostate cancer after KT, while HLA-DR 1-mismatch and 2-mismatch were both risk factors of prostate cancer after KT. This research contributed to the focus on the relationship between induction therapy and cancer occurrence after KT, and also provide guidance for reasonable selections of HLA typing of prostate cancer before KT.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-09-10
DOI
https://doi.org/10.3389/fonc.2025.1562869
Citations
1
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
1.99

Funders

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article

Analyzing the impact of human leukocyte antigen mismatch on the incidence of prostate cancer and the advantage of T cell therapy in patients after kidney transplantation based on the United Network for Organ Sharing database

Jia-Xi Mao, Shangxi Fu, Yang Gao, Jingjing Li et al.
1 citations
Frontiers in Oncology
Renal Transplantation Outcomes and Treatments
1.99
article

Analyzing the impact of human leukocyte antigen mismatch on the incidence of prostate cancer and the advantage of T cell therapy in patients after kidney transplantation based on the United Network for Organ Sharing database

Jia-Xi Mao, Shangxi Fu, Yang Gao, Jingjing Li, Wenyuan Guo, Aijun Jiang
article en
1 citations

Abstract

From the perspective of prostate cancer occurrence after transplantation, the use of T cell therapy is of great significance. HLA mismatch ≥ 3 was a risk factor of prostate cancer after KT. HLA-A and HLA-B 2-mismatch were risk factors of prostate cancer after KT, while HLA-DR 1-mismatch and 2-mismatch were both risk factors of prostate cancer after KT. This research contributed to the focus on the relationship between induction therapy and cancer occurrence after KT, and also provide guidance for reasonable selections of HLA typing of prostate cancer before KT.

Frontiers in OncologyVol. 15
Ruijin Hospital (CN), Shanghai Changzheng Hospital (CN), People's Liberation Army 411 Hospital (CN)
Chinese People’s Liberation Army
Openalex Percentile: Top 12%
Renal Transplantation Outcomes and Treatments
1.99
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Analyzing the impact of human leukocyte antigen mismatch on the incidence of prostate cancer and the advantage of T cell therapy in patients after kidney transplantation based on the United Network for Organ Sharing database — Jia-Xi Mao, Shangxi Fu, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS