Hashimoto’s encephalopathy in psychiatric inpatients: neuropsychiatric morbidity, diagnostic challenges and treatment

In conclusion, HE manifests as a distinct and severe neuropsychiatric syndrome in a subset of seropositive psychiatric inpatients. The emergence of a late-onset clinical picture characterized by a delirium-catatonia complex, particularly when refractory to conventional psychiatric treatment, warrants a high index of suspicion for HE. A multimodal diagnostic approach is essential for accurate identification, enabling the timely initiation of immunotherapy to ameliorate severe neuropsychiatric morbidity and prevent long-term disability.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2025-09-10
DOI
https://doi.org/10.3389/fpsyt.2025.1639179
Citations
1
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
1.39
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article

Hashimoto’s encephalopathy in psychiatric inpatients: neuropsychiatric morbidity, diagnostic challenges and treatment

Burçin Çolak, Özlem Akgün Doğan, Rezzak Yılmaz, Meram Can Saka et al.
1 citations
Frontiers in Psychiatry
Autoimmune Neurological Disorders and Treatments
1.39
article

Hashimoto’s encephalopathy in psychiatric inpatients: neuropsychiatric morbidity, diagnostic challenges and treatment

Burçin Çolak, Özlem Akgün Doğan, Rezzak Yılmaz, Meram Can Saka, Sena Ünal, Yağmur Kır, Berker Duman, Güle Çınar, Kazım Cihan Can, Mine Araz, Şeyda Erdoğan, Şafak Yalçın Şahiner, Emine Uslu, Canan Yücesan, Rıfat Serav İlhan
article en
1 citations

Abstract

In conclusion, HE manifests as a distinct and severe neuropsychiatric syndrome in a subset of seropositive psychiatric inpatients. The emergence of a late-onset clinical picture characterized by a delirium-catatonia complex, particularly when refractory to conventional psychiatric treatment, warrants a high index of suspicion for HE. A multimodal diagnostic approach is essential for accurate identification, enabling the timely initiation of immunotherapy to ameliorate severe neuropsychiatric morbidity and prevent long-term disability.

Frontiers in PsychiatryVol. 16
Ankara University (TR)
Openalex Percentile: Top 16%
Autoimmune Neurological Disorders and Treatments
1.39
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