Identification of clinically relevant multi-drug resistant ESKAPEE isolates from hospital wastewater surveillance in Thailand
Our results show that surveillance of untreated hospital wastewater is capable of identifying ESKAPEE that share similar drug resistance profiles, AMR genes, and clonal lineages found in the clinical isolates over the same time period. To our knowledge, this is one of the first studies to demonstrate a high level of genetic-relatedness between hospital wastewater and clinical isolates and demonstrate the clinical relevance of bacterial wastewater surveillance for MDR ESKAPEE pathogens.
Authors
- Nattaya Ruamsap (ORCID: https://orcid.org/0000-0001-6527-0480)
- Jeffrey Livezey (ORCID: https://orcid.org/0000-0001-9748-095X)
- Tanit Boonsiri (ORCID: https://orcid.org/0000-0001-8102-0879)
- Melissa J. Martin (ORCID: https://orcid.org/0000-0002-8772-9392)
- Daniel M. Boudreaux
- Paphavee Lertsethtakarn (ORCID: https://orcid.org/0000-0003-2993-9794)
- Katie Bartlett (ORCID: https://orcid.org/0009-0007-3117-5048)
- Pattaraporn Vanachayangkul
- Kirakarn Kirativanich
- Anjali P. Sapre
- Sirigade Ruekit
- Chatchadaporn Thamnurak
- Sidhartha Chaudhury (ORCID: https://orcid.org/0000-0001-9513-6688)
- Wilawan Oransathit
- Dutsadee Peerapongpaisarn
- Wirote Oransathit
- Yutthana Thanyathada
- Chantida Pradipol
Institutions
- Queen Sirikit National Institute of Child Health (TH)
- Phramongkutklao Hospital (TH)
- Armed Forces Research Institute of Medical Science (TH)
- Chonburi Hospital (TH)
- Phramongkutklao College of Medicine
- Walter Reed Army Institute of Research (US)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-09-10
- DOI
- https://doi.org/10.3389/fmicb.2025.1657219
- Citations
- 2
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.18