Endometrial carcinoma in Kenya: clinical and biomarker profiles of 123 cases seen at two tertiary referral centers

This study provides a comprehensive clinicopathologic and immunophenotypic profile of EC in a Kenyan population. The predominance of endometrioid carcinoma and the frequent loss of MMR proteins in this subgroup align with global trends. However, the high proportion of p53-abnormal tumors, particularly among serous carcinomas, suggests a significant presence of biologically aggressive disease. These findings highlight the utility of IHC as a practical and informative tool for subtype classification and risk stratification in resource-limited settings.