Safety and efficacy evaluation of low-dose of esketamine combined with propofol for painless gastroscopy: a single-center, randomized, double-blind, parallel controlled clinical trial
Considering the superior safety and efficacy observed in the PE2 group, we recommend the combination of 2 mg/kg propofol and 0.1 mg/kg esketamine as the optimal anesthesia for painless gastroscopy. This combination provides several benefits, including reduced reflex cough, stable hemodynamics, and faster recovery, making it a valuable clinical practice.
Authors
- Ruo‐Xu Gu (ORCID: https://orcid.org/0000-0003-2587-0232)
- Yongfa Zhang (ORCID: https://orcid.org/0000-0003-0853-0201)
- Xiaoyu Zhuang (ORCID: https://orcid.org/0000-0002-5826-1161)
- Lin Zhang (ORCID: https://orcid.org/0000-0003-3985-1374)
- Xiaoyu Huang (ORCID: https://orcid.org/0000-0002-3672-1980)
- Shaoping Wu
Institutions
- Shantou University (CN)
- Deyang Stomatological Hospital (CN)
- Second Affiliated Hospital of Shantou University Medical College (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-09-10
- DOI
- https://doi.org/10.3389/fmed.2025.1606134
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00