A comprehensive analysis reveals the relationship between artificial sweeteners and prostate cancer
By integrating bioinformatics, machine learning, molecular docking, and <i>in vitro</i> cellular assays, this study demonstrates that ASs inhibit PCa progression through multiple molecular targets and signaling pathways. Collectively, these findings provide important insights into the safety assessment of food additives and cancer risk assessment.
Authors
- Pudong Gao
- Bangwei Che
- Wei Li (ORCID: https://orcid.org/0000-0001-9931-5990)
- Kuiyuan Zhang
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-09-10
- DOI
- https://doi.org/10.3389/fnut.2025.1646623
- Citations
- 2
- Primary Topic
- Biochemical Analysis and Sensing Techniques
- Type
- article
- Field-Weighted Citation Impact
- 2.24