Inner Limiting Membrane Peel Extends In Vivo Calcium Imaging of Retinal Ganglion Cell Activity Beyond the Fovea in Non-Human Primate
Peeling the ILM is a viable strategy to expand viral access to RGCs for gene therapy, and when paired with GCaMP imaging has the potential to advance visual neuroscience, preclinical evaluation of retinal function, detection of vision loss, and assessment of therapeutic interventions.
Authors
- David DiLoreto (ORCID: https://orcid.org/0000-0002-1787-8069)
- Juliette E. McGregor (ORCID: https://orcid.org/0000-0002-8046-028X)
- Vamsi K. Gullapalli (ORCID: https://orcid.org/0000-0002-2779-0909)
- Sara S. Patterson (ORCID: https://orcid.org/0000-0003-4574-3935)
- Amber D. Walker
- Rachel Hollar
- Hector Baez (ORCID: https://orcid.org/0000-0001-7055-0559)
- William S. Fischer (ORCID: https://orcid.org/0000-0003-3574-5494)
- Jennifer M. LaPorta
Institutions
- University of Rochester Medical Center (US)
- University of Rochester (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-09-10
- DOI
- https://doi.org/10.1167/iovs.66.12.25
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Research to Prevent Blindness
- University of Pennsylvania
- University of Rochester
- National Institutes of Health
- Perelman School of Medicine, University of Pennsylvania