Actionable Genes and Carcinogenic Pathways for Gastric Cancer in Latinos
This study shows that the unique genetic landscape of GC tumors in this group may lead to more aggressive cases and affect treatment responses, contributing to higher mortality rates. The higher mutation rates in biomarkers related to prognosis and therapy suggest that further research might uncover additional susceptibility variants. This underscores the importance of including Hispanics in genomic studies to better understand the genetic pathways associated with the risk and progression of GC.
Authors
- Ingrid M. Montes‐Rodríguez (ORCID: https://orcid.org/0000-0002-3289-9597)
- Marcia Cruz‐Correa (ORCID: https://orcid.org/0000-0001-8147-7457)
- Hilmaris Centeno‐Girona (ORCID: https://orcid.org/0000-0002-2271-4560)
- Noridza Rivera
- Sol V. Pérez‐Mártir
Institutions
- University of Puerto Rico, Medical Sciences Campus (PR)
- University of Puerto Rico System (PR)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/cam4.71216
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of General Medical Sciences