ICTUSCOG: Poststroke cognitive impairment following nondisabling stroke: Study protocol of a spanish multicentre prospective cohort study
The study will quantify the incidence of early and late PSCI, identify predictors of progression, and characterise cognitive profiles. Multivariate models and clustering techniques will explore interactions among clinical, biological and imaging data. A predictive model will be developed and validated for clinical use. ICTUSCOG will provide critical insights into the mechanisms and trajectories of PSCI, informing prevention, early intervention, and rehabilitation strategies. The work aims to establish predictive tools and care pathways to mitigate the burden of cognitive impairment in stroke survivors.
Authors
- H. Tejada Meza (ORCID: https://orcid.org/0000-0002-6506-1037)
- E Marta-Moreno
- M.A. Marín-Cárdenas
- C. Moreno Loscertales (ORCID: https://orcid.org/0000-0002-4423-9393)
- M Serrano-Ponz
- Javier Marta-Moreno (ORCID: https://orcid.org/0000-0003-3574-3034)
- Esther Sierra‐Martínez
- Fidel Alfaro‐Almagro (ORCID: https://orcid.org/0000-0002-9133-5951)
- Jorge Andrés Navarro (ORCID: https://orcid.org/0000-0001-6148-0667)
- Marta Palacín-Larroy
- Patricia de la Riva (ORCID: https://orcid.org/0000-0001-6542-868X)
- M. Bautista Lacambra (ORCID: https://orcid.org/0000-0002-6734-943X)
- Isabel Campello-Morer
- Gonzalo Forno-Martinic
- Raquel Laspiur Gándara
- Paula Canasto-Jiménez
Institutions
- Universidad de Zaragoza (ES)
- University of Oxford (GB)
- Biogipuzkoa Health Research Institute (ES)
- Wellcome Centre for Integrative Neuroimaging (GB)
- Hospital Universitario Miguel Servet (ES)
- Hospital San Juan de Dios (CL)
- Instituto de Neurociencia Biomédica (CL)
- Instituto de Investigación Sanitaria Aragón (ES)
- Onkologikoa (ES)
- Center for Climate and Resilience Research (CL)
- University of Chile (CL)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1371/journal.pone.0330255
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Gobierno de Aragón