Comprehensive analysis of disulfidptosis-related genes in pulmonary hypertension through machine learning and immune infiltration: Spotlight on USP32 and ZNF655 as key regulators
This study elucidates the contributory role of USP32 and ZNF655 in the pathogenesis of PAH, making them as critical genes within the disulfidptosis pathway.
Authors
- Riken Chen (ORCID: https://orcid.org/0000-0001-6101-7891)
- Jiahua Pan (ORCID: https://orcid.org/0000-0001-6363-6522)
- Sumeng Qi (ORCID: https://orcid.org/0009-0007-2020-8000)
- Guojun Yang
- Xishi Sun (ORCID: https://orcid.org/0000-0003-3841-4789)
- Jihuang Huang
- Junfen Cheng (ORCID: https://orcid.org/0000-0003-3130-7948)
- Jie Sun (ORCID: https://orcid.org/0000-0002-4654-3081)
- Lingpin Pang
- Tao Huang (ORCID: https://orcid.org/0000-0003-1743-1942)
- Wenliang Chen (ORCID: https://orcid.org/0000-0001-5141-325X)
- Xing Zeng (ORCID: https://orcid.org/0009-0002-4672-1439)
- Dingyu Guo (ORCID: https://orcid.org/0009-0000-7525-6615)
- Xian Qian
Institutions
- Guangdong Medical College (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Central People's Hospital of Zhanjiang (CN)
- Qujiang People's Hospital (CN)
- Affiliated Hospital of Guangdong Medical College Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-09
- DOI
- https://doi.org/10.1371/journal.pone.0330832
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00