Prevalence and predictors of viral load non-suppression among adolescents on dolutegravir-based antiretroviral therapy: A cross-sectional study from three urban clinics, Soroti City

Nearly one in five adolescents on DTG-based ART in Soroti City had viral non-suppression, despite optimized treatment regimens. Targeted interventions-particularly enhanced adherence counseling for older and male adolescents, expanding MMD coverage, and provision of fixed-dose regimens-are urgently needed to improve VLS among ALHIV. These findings underscore the need for adolescent-centered HIV care strategies to close the viral suppression gap and advance progress towards epidemic control.

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Publication Details

Journal
PLoS ONE
Published
2025-09-09
DOI
https://doi.org/10.1371/journal.pone.0331835
Citations
1
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
1.40
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article

Prevalence and predictors of viral load non-suppression among adolescents on dolutegravir-based antiretroviral therapy: A cross-sectional study from three urban clinics, Soroti City

Abraham Ignatius Oluka, Simple Ouma, Victoria Nankabirwa, John Bosco Isunju et al.
1 citations
PLoS ONE
HIV/AIDS Research and Interventions
1.40
article

Prevalence and predictors of viral load non-suppression among adolescents on dolutegravir-based antiretroviral therapy: A cross-sectional study from three urban clinics, Soroti City

Abraham Ignatius Oluka, Simple Ouma, Victoria Nankabirwa, John Bosco Isunju, Saadick Mugerwa Ssentongo, Boniface Oryokot, Connie Nait, Raymond Kusiima
article en
1 citations

Abstract

Nearly one in five adolescents on DTG-based ART in Soroti City had viral non-suppression, despite optimized treatment regimens. Targeted interventions-particularly enhanced adherence counseling for older and male adolescents, expanding MMD coverage, and provision of fixed-dose regimens-are urgently needed to improve VLS among ALHIV. These findings underscore the need for adolescent-centered HIV care strategies to close the viral suppression gap and advance progress towards epidemic control.

PLoS ONEVol. 20(9)
The AIDS Support Organization (UG), AIDS Information Centre (UG), Makerere University (UG)
Openalex Percentile: Top 16%
HIV/AIDS Research and Interventions
1.40
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