The Efficacy and Safety of Teprotumumab in Geriatrics Patients: A Multicenter Study

Teprotumumab is effective in reducing clinical activity score and proptosis in geriatric thyroid eye disease patients with short-term follow-up; however, high rates of adverse events, reactivation, and proptosis regression over time warrant extreme caution and selective use in this population.

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Publication Details

Journal
Ophthalmic Plastic and Reconstructive Surgery
Published
2025-09-09
DOI
https://doi.org/10.1097/iop.0000000000003024
Citations
1
Primary Topic
Ophthalmology and Eye Disorders
Type
article
Field-Weighted Citation Impact
1.47
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article

The Efficacy and Safety of Teprotumumab in Geriatrics Patients: A Multicenter Study

Madhura A. Tamhankar, Andrea L. Kossler, Kimberly Cockerham, Sara Tullis Wester et al.
1 citations
Ophthalmic Plastic and Reconstructive Surgery
Ophthalmology and Eye Disorders
1.47
article

The Efficacy and Safety of Teprotumumab in Geriatrics Patients: A Multicenter Study

Madhura A. Tamhankar, Andrea L. Kossler, Kimberly Cockerham, Sara Tullis Wester, Rafael Rubio, Amina Malik, Benyam Kinde, Patcharaporn Chandraparnik, Evan Meyer, Andrew R. Harrison, Taylor Linaburg, Connie M. Sears, Linus Amarikwa, Ridhima Guniganti, Melissa Goldin, Roman Shinder, Daniel B. Rootman, Hannah Walsh, Louise A. Mawn, Chrysoula Dosiou, Shreya Shah, Steven M. Couch, Suyoung Choi, Karmouta Reem
article en
1 citations

Abstract

Teprotumumab is effective in reducing clinical activity score and proptosis in geriatric thyroid eye disease patients with short-term follow-up; however, high rates of adverse events, reactivation, and proptosis regression over time warrant extreme caution and selective use in this population.

Ophthalmic Plastic and Reconstructive SurgeryVol. 42(1)
Barnes-Jewish Hospital (US), University of Minnesota (US), SUNY Downstate Health Sciences University (US), Vanderbilt University (US), Phramongkutklao Hospital (TH), Methodist Hospital (US), Doheny Eye Institute (US), Jewish Hospital (US), Smith-Kettlewell Eye Research Institute (US), Phramongkutklao College of Medicine, University of Nebraska Medical Center (US), University of Pennsylvania (US), Stanford University (US)
Openalex Percentile: Top 15%
Ophthalmology and Eye Disorders
1.47
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