Vaccination Recommendations in Patients With Atopic Dermatitis Treated With <scp>JAK</scp> Inhibitors

Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine administration. This document aims to provide dermatologists and other healthcare practitioners with comprehensive practical vaccination recommendations for adults and adolescent patients with atopic dermatitis who are receiving or are about to receive treatment with JAK inhibitors. While inactivated vaccines are safe and recommended during JAK treatment, live attenuated vaccines are contraindicated unless treatment is temporarily discontinued according to clinical guidelines. It is crucial to follow vaccination guidelines established by official agencies and tailor them to individual patient needs. Careful consideration and follow-up are essential to ensure patient safety and optimal therapeutic outcomes.

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Publication Details

Journal
International Journal of Dermatology
Published
2025-09-10
DOI
https://doi.org/10.1111/ijd.70033
Citations
3
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
6.01

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article

Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors

Ricardo Ruíz‐Villaverde, Irene Hernández‐Martín, E. Serra‐Baldrich, Mariano Ara‐Martín et al.
3 citations
International Journal of Dermatology
Dermatology and Skin Diseases
6.01
article

Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors

Ricardo Ruíz‐Villaverde, Irene Hernández‐Martín, E. Serra‐Baldrich, Mariano Ara‐Martín, Carolina Moreno, María del Pilar Fortes
article en
3 citations

Abstract

Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine administration. This document aims to provide dermatologists and other healthcare practitioners with comprehensive practical vaccination recommendations for adults and adolescent patients with atopic dermatitis who are receiving or are about to receive treatment with JAK inhibitors. While inactivated vaccines are safe and recommended during JAK treatment, live attenuated vaccines are contraindicated unless treatment is temporarily discontinued according to clinical guidelines. It is crucial to follow vaccination guidelines established by official agencies and tailor them to individual patient needs. Careful consideration and follow-up are essential to ensure patient safety and optimal therapeutic outcomes.

International Journal of DermatologyVol. 65(2)
Universitat Autònoma de Barcelona (ES), Hospital de Sant Pau (ES), Hospital Universitario de Getafe (ES), Instituto de Investigación Biosanitaria de Granada (ES), Hospital Clínico Universitario Lozano Blesa (ES), Instituto de Investigación Sanitaria Aragón (ES), Pfizer (Spain) (ES)
Pfizer
Openalex Percentile: Top 4%
Dermatology and Skin Diseases
6.01
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Vaccination Recommendations in Patients With Atopic Dermatitis Treated With <scp>JAK</scp> Inhibitors — Ricardo Ruíz‐Villaverde, Irene Hernández‐Martín, et al. · International Journal of Dermatology (2025) | TGRS Research Map | TGRS